Lipids and Lipid Derivatives
Medchemexpress LLC Incensole Acetate | 34701-53-6 | 1 MG
Incensole Acetate, a main constituent of Boswellia carterii resin, demonstrates neuroprotective effects against neuronal damage from traumatic and ischemic head injury. It has been shown to reduce Aβ25-35-triggered apoptosis in hOBNSCs and, in in vitro studies, significantly ameliorates Aβ25-35-induced cell death.
- Demonstrates neuroprotective effects against neuronal damage
- Reduces Aβ25-35-triggered apoptosis in hOBNSCs
- Ameliorates Aβ25-35-induced cell death in in vitro studies
- High purity of 99.08%
- Soluble in DMSO
Medchemexpress LLC Iso-VQA-ACC acetate | 99.48% | 625.63 (free base) | 1 MG
iso-VQA-ACC acetate is a substrate for constitutive proteasome, characterized by its molecular formula C29H35N7O9.xC2H4O2 and a molecular weight of 625.63 (free base). This compound has a purity of 99.48% and is commonly identified by its sequence, iso-Val-Gln-Ala-{ACC}. It is primarily used in research involving proteasome and metabolic enzyme/protease pathways.
- Targets proteasome activity for metabolic studies.
- High purity suitable for sensitive research applications.
- Soluble in DMSO at 100 mg/mL, requiring ultrasonic treatment for dissolution.
Medchemexpress LLC MK2-IN-5 acetate (Hsp25 kinase inhibitor acetate) | 99.64% | 1396.68 | 10 MG
MK2-IN-5 acetate (Hsp25 kinase inhibitor acetate) is a Mk2 pseudosubstrate with a Ki of 8 μM. It targets the protein interaction domain in the MAPK pathway and inhibits HSP25 and HSP27 phosphorylation. In vitro, MK2-IN-5 acetate (5-10 μM, 2 hours) inhibits TGF-β1 induced connective tissue growth factor (CTGF) and collagen type I in primary human keloid fibroblasts. In vivo, a single intraperitoneal injection of 2 mg/kg of MK2-IN-5 acetate decreased HSP25 phosphorylation in a ventilator-associated lung injury model.
Medchemexpress LLC Pregnenolone acetate | 1778-02-5 | 98.4% | 1 ML
Pregnenolone acetate is a nonmetabolized Pregnenolone analog that promotes neurite extension and induces changes in growth cone morphology in primary cultures of cerebellar granule neurons. It is a neurosteroid that increases microtubule polymerization and shows potential for neurodevelopmental diseases research.
- Promotes neurite extension
- Induces changes in growth cone morphology
- Increases microtubule polymerization
- Potential for neurodevelopmental diseases research
Medchemexpress LLC (-)-Bornyl acetate | 5655-61-8 | 196.29 | 10 G
Isolated from hyssop oil, (-)-Bornyl acetate (L-(-)-Bornyl acetate) is an antifungal agent. It is a less active enantiomer of (+)-Bornyl acetate. Wavy roots from seedlings exposed to (-)-bornyl acetate are significantly longer than those from seedlings exposed to (+)-bornyl acetate. When applied individually to barley seedlings, (-)-Bornyl acetate reduced powdery mildew infection compared to controls without ether.
- Isolated from hyssop oil
- Antifungal activity
- Less active enantiomer of (+)-Bornyl acetate
Medchemexpress LLC Trometamol acetate | 6850-28-8 | 99.0% | 25 G
Trometamol acetate (Tromethamine acetate) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. It is an effective amine compound for pH control in the physiological range.
- Biologically inert amino alcohol
- Low toxicity
- Buffers carbon dioxide and acids in vitro and in vivo
- Effective amine compound for pH control in physiological range
Medchemexpress LLC Megestrol acetate (Standard) | 595-33-5 | 98.5% | 384.51 | 50 MG
Megestrol acetate (Standard) is the analytical standard of Megestrol acetate, intended for research and analytical applications. It is a synthetic and orally active progesteronal agent. This product is effective as an appetite stimulant for wasting syndromes like cachexia and decreases nuclear and cytosol androgen receptors in human BPH tissue. It also has potential for HIV study and downregulates the autophagic catabolic pathway.
- Effective as an appetite stimulant for wasting syndromes
- Decreases nuclear and cytosol androgen receptors in human BPH tissue
- Potential for HIV study
- Downregulates the autophagic catabolic pathway
- Suitable for qualitative, quantitative, and methodological research in HPLC, GC, and MS
Cayman Chemical DL-Tryptophn octyl esterhy 5g
A stable, cell-permeable tryptophan derivative with an octyl ester protected COOH group
Apexbio Technology LLC Oxytocin acetate 6233-83-6 10mg
Oxytocin acetate (CAS 6233-83-6) is an acetate salt form of oxytocin a neuropeptide synthesized primarily in hypothalamic regions including the paraventricular and supraoptic nuclei Biologically oxytocin acts as a positive allosteric modulator of the -opioid receptor (MOR) enhancing receptor-mediated signaling without directly activating MOR or altering opioid ligand affinity In vitro studies with hMOR-expressing HEK293 cells indicate oxytocin augments signaling induced by MOR agonists such as endomorphin-1 morphine and fentanyl Its intracerebroventricular administration increases neuronal activity in rat nucleus accumbens shell highlighting potential roles in pain modulation social behavior and addiction research
Apexbio Technology LLC Megestrol Acetate 595-33-5 10mM (in 1mL DMSO)
Megestrol Acetate (CAS 595-33-5) is a synthetic progestin utilized to downregulate nuclear and cytoplasmic androgen receptor activity It modulates hormone receptor-mediated processes thereby impacting cellular metabolic and signaling pathways Megestrol Acetate exerts its biological activity primarily by inducing apoptosis and disrupting cell cycle progression In in vitro studies using HepG2 cell lines Megestrol Acetate demonstrates proliferation inhibition with an IC50 value of approximately 260 M Based on these pharmacological properties Megestrol Acetate holds research potential in studies of cancer cachexia hepatocellular carcinoma and the investigation of tumor growth mechanisms
Cambridge Isotope Laboratories Mono-n-octyl phthalate (unlabeled) 100 ug/mL in MTBE 1 2 mL
Mono-n-octyl phthalate (unlabeled) 100 ug/mL in MTBE 1 2 mL
Medchemexpress LLC Delmitide acetate | 501019-16-5 | 99.2% | 1288.62 g/mol | C61H109N17O13 | 50 MG
Delmitide acetate is an orally active D-isomer decapeptide with potent anti-inflammatory activity. It inhibits production of TNF-α, IFN-γ, and interleukin-12, and up-regulates heme oxygenase-1 activity. It is provided for research use in studies of inflammatory diseases such as ulcerative colitis.
- Orally active d-isomer decapeptide.
- Potent inhibition of proinflammatory cytokines (TNF-α, IFN-γ, IL-12).
- Up-regulates heme oxygenase-1 activity.
- Suitable for inflammatory disease research applications.
- Supplied as an acetate salt with reported high purity.
eMolecules ChemScene / Palmityl acetate / 250mg / 649803498 / CS-0185766 / 0.000 / 629-70-9 / MFCD00056152 / 284.484 / C18H36O2
ChemScene / Palmityl acetate / 250mg / 649803498 / CS-0185766 / 0.000 / 629-70-9 / MFCD00056152 / 284.484 / C18H36O2
Cayman Chemical DLTryptophn octyl esTRhy 500mg
A stable, cell-permeable tryptophan derivative with an octyl ester protected COOH group
AdipoGen Ulipristal acetate
Chemical. CAS 126784-99-4. Formula C30H37NO4. MW 475.62. Synthetic. Ulipristal acetate is a selective progesterone receptor modulator SPRM that binds to the human progesterone receptors PR-A and PR-B EC50s=8.5 and 7.7nM, respectively, rabbit uterine PR EC50=13.6nM, and rabbit thymic glucocorticoid receptor GR EC50=15.4nM. It is selective for human progesterone receptors over the human estrogen receptor ER EC50>10,000nM. It inhibits growth of IGROV-1 and SKOV3 human ovarian cancer cells IC50s=15.5 and 31.5µM, respectively even after resistance to combined cisplatin and paclitaxel treatment has developed. Ulipristal acetate reverses the proliferative effect of progesterone on patient-derived germline mutant BRCA1 breast tissue xenografts in ovariectomized athymic mice. Formulations containing ulipristal acetate have been used as emergency contraceptives and to treat uterine fibroids.